Blood type or blood group is determined, in part, by the abo blood group antigens present on red blood cells. Blood bank software is available in webbased online versions. Abod blood groups austin community college district. Bold letters beside each well designate major blood types and rho factors to prevent errors. Blood typing ppt blood type dominance genetics free. Blood grouping and crossmatching is one of the few important tests that the anaesthesiologist orders during perioperative period. Abo blood grouping introduction terry kotrla, ms, mtascpbb abo basics blood group antigens are actually sugars attached to the red blood cell. Although some references will be made to the molecular structures, the detailed molecular structures and recent advances in dna. Blood is the red liquid in the body that serves as a transporter medium for oxygen and nutrients to the cells and carrying away carbon dioxide and other various waste products. Global blood collection and processing supplies industry. There are four main blood groups a, b, ab and o, which are determined by the presence or absence of antigens and antibodies on the surface of our red blood cells.
Rh blood group is assigned the prefix 004 each antigen assigned to the rh blood group is given a unique number to complete the six digit number. Consistency is the hallmark of quality and can be achieved only through the use of standard operating procedures sops by all staff engaged in blood centres at all times. Blood group genotyping molecular blood typing grifols. A dyeassisted paperbased pointofcare assay for fast and. By the time a person is six months old, he naturally will have developed antibodies against the antigens his red blood cells lack. Among the 35 officially recognized blood group systems, the abo and rhesus rh systems receive the most attention because of the high mortality originating from mismatched aborh blood transfusion reactions 35. The abo system is the main blood grouping system behind the principle that helps classify people into one of the following four groups, i. Rh blood group system, system for classifying blood groups according to the presence or absence of the rh antigen, often called the rh factor, on the cell membranes of the red blood cells erythrocytes. Blood processing devices and consumables market size, industry share, trends, approaches and forecast to 2029 published.
Accordingly, a 70kilogram person will have 5 to 6 litres of blood. The right hand side contains antib which reacts with the cell. The basic building aim is to provide blood donation service to the city recently. History of the rh system levine and stetson 1939 described a hemolytic transfusion reaction in an obstetric patient following delivery of stillborn infant. Blood group, classification of blood based on inherited differences in antigens on the surfaces of the red blood cells. Landsteiners law if an antigen is present on a patients red blood cells, the corresponding antibody will not be present in the patients plasma.
Bombay blood group rare type of blood group h antigen is absent. Also called rhesusrh system 85% of the population is rh. It can be used in blood donation camps and in case of an emergency. United states industry consensus standard for the uniform labeling of blood and blood components using isbt 128. The left hand of the slide contains antia does not react with the unknown cell.
Blood establishment computer system validation in the users. Hence, a proper understanding of the blood group system, their clinical significance, typing and crossmatching tests, and current perspective are of paramount importance to prevent transfusionrelated complications. This meant that if a person inherited one a group gene and one b group gene their red cells would possess both the a and b blood group antigens. The plasma contains antia,antib,and antih antibodies. Aug 09, 2012 this is one of the older methods of checking blood group, column technique sephadex gel and solid phase tests have generally replaced it. What are the procedures and techniques of blood grouping. Duffy blood group system, classification of human blood based on the presence of glycoproteins known as fy antigens on the surface of red blood cells. An ebook reader can be a software application for use on a computer such as. Med tek disposotype blood typing slides blood typing. The ab blood type has both a and b antigens, and the o blood type has neither a nor b antigen.
Cellavision advanced rbc application subject to camera and system computer compatability specifications are subject to change without notice. Patient blood management market forecast to 2024 by. Blood group o is termed as blood group zero in some countries. Blood group blood group the importance of antigens and antibodies. A blood type also called a blood group is a classification of blood, based on the presence and absence of antibodies and inherited antigenic substances on the surface of red blood cells rbcs. Principle of blood grouping 2 these naturally occurring abs are mostly igm class. As the knowledge of new blood group system increased, so did the search for more sensitive pretransfusion compatibility testing methods. Blood group ab if you belong to the blood group ab, you have both a and b antigens on the surface of your rbcs and no a or b antibodies at all in your blood plasma. Feb 25, 2017 a blood type also called a blood group is a classification of blood based on the presence and absence of antibodies and also based on the presence or absence of inherited antigenic substances on.
The most wellknown classification, the abo blood group system, was developed by austrianborn american biologist karl landsteiner in 1901. The terminal carbohydrate epitopes denoting blood group h, a, and b antigens are highlighted in amber. Blood group the importance of antigens and antibodies. A blood transfusion is the infusion of whole blood or a blood component such as plasma, red blood cells, or platelets into the patients venous circulation. Theyll give your presentations a professional, memorable appearance the kind of sophisticated look that todays audiences expect. Today, safe blood transfusion is greatly attributed to the pioneering efforts of karl landsteiner on human bgs. The source of blood group antigens is the water soluble substances that are present in most body fluids and organs of a secretor. Polymethyl methacrylate pmma based point of care poc for aborhd blood grouping by the naked eye was investigated. Blood collection, processing, management devices, and. Winner of the standing ovation award for best powerpoint templates from presentations magazine. The alleles for blood group are in the same place on the chromosome 9. At present, many japanese still believe in a blood type theory. This helps you give your presentation on blood donation in a conference, a school lecture, a business proposal, in a webinar and business and professional representations.
Rh d blood group conversion using transcription activator. The abo grouping system is classified into four types based on the presence or absence of antigens on red blood cells surface and plasma antibodies. Blood group share and discover knowledge on linkedin slideshare. In this respect, synthetic antibodies generated by molecular imprinting are cost effective and offer an expedient way for abo blood group typing. The red blood cells contain hemoglobin, a protein that binds oxygen. Ppt other blood groups powerpoint presentation free to. Performing both forward and reverse grouping provides a check for accuracy.
Blood grouping share and discover knowledge on linkedin. History karl landsteiner discovered the abo blood group system in 1901 he and his five coworkers began mixing each others red cells and serum together and inadvertently performed the first forward and reverse abo groupings 3. In fact, several studies were also conducted in other countries like united states, korea, and united kingdom. Easy to switch views to enable single cell filtering and grouping adjust magnification of cell images. Introduction to the rhesus blood group university of utah.
Some of these antigens are also present on the surface of other types of cells of. This means that blood type a contains b antibodies. The type of sugar added determines the blood group. Slide blood typing group b an unknown rbc suspension is added to known antisera. An ebook reader can be a software application for use on a. As a pilot study, a total of blood samples 650 blood donors and 350 recipient patients were selected for comparison of abo and rh blood grouping by the ctt and by the automated microplate lyra system. Kell blood group system, classification of human blood based on the presence on the surfaces of red blood cells of various antigens encoded by the kel gene. This products resides on a fisher scientific gsa or va contract. Hospitalsoftwareshop blood bank software hospitalsoftwareshop provides blood bank software which is very friendly, stable and easy to use, covers endtoend modules. Compared to women with blood group o, women with blood group ab or b had a nonsignificant 38% increase in ovarian cancer incidence 95% ci 0. Blood safety and blood donor motivation powerpoint presentation. The red blood cells are the components that help in determining a persons blood type. Types of blood groups and their characteristics styles.
Dec 31, 2015 traditional blood typing methods are simple, sensitive and reliable, yet time consuming and labor intensive. Blood group genotyping for human erythrocyte antigens overcomes blood grouping limitations by looking directly into the dna sequence and thereby avoiding any donor cell or patient antibody interference. Components of blood include red blood cells rbc, platelets, white blood cells wbc and numerous clotting factors suspended in a fluid called plasma. The total blood volume makes up about 68 percent of the bodys weight. Polymethyl methacrylate pmma point of care for aborhd.
Abo blood types are also present in some other animals for example rodents and apes such as chimpanzees, bonobos and gorillas. Blood group systems definition of blood group systems by. Almost half of the uk population 48% has blood group o. A blood type blood group is defined as the classification of blood based on the presence or absence of inherited antigenic substances on the surface of red blood cells rbcs. There are 8 common blood types, as determined by presence or absence of certain antigens substances that can trigger an immune response if they are foreign to the. Slide test is quick and needs only simple equipment. Rapid and accurate blood grouping plays a critical role in multiple scientific disciplines, particularly in the biological and medical sciences 1, 2.
Reverse blood grouping is a procedure to confirm abo blood group based on the presence or absence of antia and antib in serum using known a and b red cells. E antigen 004003 advantage over rosenfield is that it is a purely. To restore intravascular volume with whole blood or albumin. Blood bank management system bbms is a webbased application that is designed to store, process, retrieve and.
These antigens may be proteins, carbohydrates, glycoproteins, or glycolipids, depending on the blood group system. Its activities include blood donations, blood grouping, antibody screening, antibody identification, cross matching, blood infectious tests, component preparation, issuing compatible blood and blood components etc. Jan 27, 2020 the us patient blood management market to hold a prominent market share during the forecast period. H antigen then serves as a substrate for a and b glycosyltransferases. Styrene plastic slides contain three deep, flat bottom, ovalshaped typing wells that permit mixing of blood and typing of sera without spillage.
Guidance manual abo and rh blood grouping document id no. April 02, 2020 published via wired release global blood processing devices and consumables market report provides a perceptive analysis with current and upcoming opportunities to. Both of these sugars are built upon the h antigenif the h antigen is left unmodified, the resulting blood group is o because neither. Type o negative red blood cells are considered the safest to give to anyone in a lifethreatening emergency or when theres a limited supply of the exact matching blood type. The reaction between red cells and corresponding antibodies usually results in clumping. The uploader spent hisher valuable time to create this blood safety and blood donor motivation powerpoint presentation slides, to share hisher useful content with the world. Red blood cells transport oxygen to, and remove carbon dioxide from, the body tissues. Pdf a study on relationship between blood group and. The relationship between achievements, intelligence.
Blood group test experiment harib diagnostic lab youtube. Individuals inherit a gene which codes for specific sugars to be added to the red cell. The samples of the donors were collected at the site of blood donation. The patient blood management market is segmented into north america, europe, asia pacific, latin america, and the middle east and africa. The process of identifying a persons blood group by serologic testing of a blood sample. Also includes details about bombay blood group and rh blood group system.
Introduction to the abo blood group system medialab, inc. However the genes have a different code giving the different blood group a b 20. Circulating blood volume will be lesser than total blood volume, because some amount of blood will be deposited in organs like liver. The eight main blood types are a, b, o, or ab, and each type can be positive or negative. This group does not have antigen a and antigen b on red blood cells.
Blood processing devices and consumables market size. Ppt abo blood grouping powerpoint presentation free to. Major errors in abo grouping, labeling, and identification of donors and recipients. Cde blood group system out of c,d and e d is the strongest antigen. The us held the major share of the global patient blood management in 2018. The abo and rh blood grouping system is based on agglutination reaction it is the reaction between antigens present on red blood cells and antibodies present in serum 30. The human blood consists of 4 main components, the red blood cells, the white blood cells, the plasma and the platelets.
Blood typing ppt free download as powerpoint presentation. Jun 16, 2015 group o dnegative blood cells are universal donors in transfusion medicine and methods for converting other blood groups into this universal donor group have been researched. Persons may thus have type a, type b, type o, or type ab blood. Mar 14, 2014 powerpoint is the worlds most popular presentation software which can let you create professional blood donation powerpoint presentation easily and in no time. It was karl landsteiner who first discovered the abo blood group bg system in 1900 and rhesus rh bg later. Ppt compatibility testing powerpoint presentation free to.
These antigens are also expressed on the surfaces of cells lining the urinary tract, where they have been identified as adhesion sites for escherichia coli bacteria, which cause urinary tract infections. Abo blood group medical genetics summaries ncbi bookshelf. Pioneer blood bankers mixed the patients serum and the donors red cells and observed for direct red blood cells lysis, agglutination, or both. Because of the lack of synthesized immunoglobulins, antia and antib in. Med tek disposotype blood typing slides blood typing slides. Slide blood typing group o the left hand of the slide contains antia does not react with the unknown cell.
As a result such person can receive blood only from a person having bombay blood type. Each blood type is named by its antigen in red blood cells. Abo blood group and rh factor determination by kit test it is the method can be used for the blood group detection principle. The a blood type has only the a antigen and the b blood type has only the b antigen.
On conduction of survey it is known that only one among 67 people has b negative blood group on an average of 1. It accompanies the dbrbc, a new ncbi resource that contains clinical and dna data about human red blood cells. What are advantages and disadvantages of each of the blood. Additional benefits of blood group genotyping include improved transfusion compatibility and reduced alloimmunization. Crossmatching will detect incompatibilities between the donor and recipient that will not be evident on blood typing. Abo blood group system, the classification of human blood based on the inherited properties of red blood cells erythrocytes as determined by the presence or absence of the antigens a and b, which are carried on the surface of the red cells.
Tile testing may be used for emergency abo grouping tests or for preliminary grouping particularly in an outdoor camp, however it should always be supplemented with a cell and serum grouping using any one of the other above mentioned techniques. Our webbased software generates for you a completely customized nutritional program designed to optimize your overall health using important markers, such as blood type. Comparison between conventional and automated techniques for. Blood consists of several types of cells floating around in a fluid called plasma. If blood is given to a patient that has a blood type that is incompatible with the blood type of the blood that the patient receives, it can cause intravenous clumping in the patients blood which can be fatal. There are four common blood groups in the abo system. P blood group system, classification of human blood based on the presence of any of three substances known as the p, p 1, and p k antigens on the surfaces of red blood cells. Armstrong introduction this section will cover the major blood group systems, some of the other blood group systems and will also include information on hla and notes on platelet antigens. The most common blood type classification system is the abo system discovered and defined by karl landsteiner in the early 1900s. Hospitalsoftwareshop software for blood bank has the usp of medical devices integration.
Blood groups and red cell antigens is a guide to the differences in our blood types that complicate blood transfusions and pregnancy. Blood grouping definition of blood grouping by medical. Blood group test kit blood grouping kit latest price. The technique is similar to abo blood grouping and hence, rh typing is done along with abo blood grouping. International society of blood transfusion numeric terminology. A blood group test is used to determine the blood group of an individual. Blood group antigens are actually sugars attached to the red blood cell. Most recipient antibodies directed against antigens on the donor red blood cells. Blood group testing an experiment to determine the blood. The blood groups are defined by the presence of specific carbohydrate sugars on the surface of red blood cells, nacetylgalactosamine for the a antigen, and dgalactose for the b antigen. Abo blood group is the most important system in blood transfusion being the only one among the blood group systems in which the antibodies are consistently and predictably present in the serum of normal person whose red cell lacks the antigen. An ebook reader can be a software application for use on a computer such as microsofts free reader. No antigen a,or antigen b, no h antigen on the red cells.
Apr 20, 2016 the abo blood group system is the most important blood type system or blood group system in human blood transfusion. If a cbc andor an antibody screening test is ordered with this test, please submit a separate 4 ml specimen for each test. After the abo system, the rh rhesus blood group system is regarded as the second most important blood group system, as some of the. Global blood collection and processing supplies markets, 2016. Evaluation of the secretor status of abo blood group. Blood bank module provides uptodate information about total daily blood component stock, total daily blood requisitions and. Blood type testing lab report nattanit trakullapphan.
Patient blood management markets, 20192024 penetration. Peter dadamo, puts the power of personalized nutrition in your hands. The global blood processing devices and consumables market is expected to reach usd 51. The abo blood group system is the most important blood type system or blood group system in human blood transfusion. Type 1 chain and type 2 chain precursors underlined are fucosylated by fut1 and fut2 fucosyltransferases to form h antigen. Abo blood group system dr r amita assistant professor dept of transfusion.
Discovered abo blood group system in 1901 discovered rh factor in 1930 along with alexander s. Reciprocal relationship between abo antigens and antibodies antigens on rbcs antibody in plasma serum blood group a antib a b antia. The designation rh is derived from the use of the blood of rhesus monkeys in the basic test for determining the presence of the rh antigen in human blood. Red blood cells rbcs or erythrocytes are differentiated from each other on the basis of their surface antigen structures. Worlds best powerpoint templates crystalgraphics offers more powerpoint templates than anyone else in the world, with over 4 million to choose from. Blood group b if you belong to the blood group b, you have b antigens on the surface of your rbcs and a antibodies in your blood plasma. The red cells of an individual contain antigens on their surfaces that correspond to their blood group and antibodies in the serum that identify and combine with the antigen sites on the surfaces of red cells of another type.